Flights from Santa Ana John Wayne Airport to Iowa

Flight deals from Santa Ana John Wayne Airport to Iowa

Looking for cheap tickets from Santa Ana John Wayne Airport to Iowa, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Flying from Santa Ana John Wayne Airport to Iowa

Arm yourself with these facts on the fly.
Cheapest flight foundSAR 528
Cheapest month to flyMarch
Average flight time3 hrs, 18 mins
Average flights per week3
Most popular airlineAllegiant Air

Frequently asked questions

Yes - direct flights currently operate from Santa Ana John Wayne Airport to Des Moines Airport in Iowa.
We looked at all of the upcoming return flights from Santa Ana John Wayne Airport to Iowa we could find over the next 12 months. It looks like SAR 528 is the best price. This is good, compared to the average Iowa ticket price of SAR 1,444.
The cheapest month to fly from Santa Ana John Wayne Airport to Fort Dodge Airport is currently February.
The cheapest month to fly from Santa Ana John Wayne Airport to Waterloo Airport is currently February.
The cheapest month to fly from Santa Ana John Wayne Airport to Des Moines Airport is currently March.
And the cheapest month to fly from Santa Ana John Wayne Airport to Cedar Rapids Airport is usually March.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santa Ana John Wayne Airport to Iowa on Friday, 6 March 2026.
If you're flying from Santa Ana John Wayne, the cheapest city in Iowa to fly into is Des Moines. The cheapest airport serving Des Moines at the moment is Des Moines.
The average flight time between Santa Ana John Wayne Airport and Iowa is 3 hours and 18 minutes.