Flights from Buffalo to South Carolina

Flight deals from Buffalo to South Carolina

Looking for cheap tickets from Buffalo to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Flying from Buffalo to South Carolina

Arm yourself with these facts on the fly.
Cheapest flight foundSAR 751
Cheapest month to flySeptember
Cheapest airport to fly fromBuffalo Niagara

Frequently asked questions

We looked at all of the upcoming return flights from Buffalo to South Carolina we could find over the next 12 months. It looks like SAR 751 is the best price. This is good, compared to the average South Carolina ticket price of SAR 1,630.
The cheapest month to fly from Buffalo to Charleston Airport is usually September. The cheapest month to fly from Buffalo to Hilton Head Airport is usually April. The cheapest month to fly from Buffalo to Greenville-Spartanburg Airport is usually May. And the cheapest month to fly from Buffalo to Columbia Metropolitan Airport is usually January.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Buffalo to South Carolina on Thursday, 10 September 2026.
Currently, there aren't any direct flights from Buffalo to South Carolina, but you can still fly with a stopover.
If you're flying from Buffalo, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.